May 2008
| Date | Transaction |
| 5/11 | Wilson Betemit (INF) - Placed on 15-Day DL, (Hamstring) |
| 5/10 | Kyle Farnsworth (RHP) - Reinstated From League Suspension |
| 5/10 | Jonathan Albaladejo (RHP) - Placed on 15-Day DL, (Right elbow) |
| 5/10 | Chris Britton (RHP) - Called Up from Minors |
| 5/9 | Kyle Farnsworth (RHP) - Starting to Serve Suspension |
| 5/9 | Chris Britton (RHP) - Sent to Minors |
| 5/9 | Kei Igawa (LHP) - Called Up from Minors |
| 5/6 | Alberto Gonzalez (INF) - Sent to Minors |
| 5/6 | Wilson Betemit (INF) - Removed From 15-Day DL, (Conjunctivitis) |
| 5/4 | Brian Bruney (RHP) - Transferred to 60-Day DL, (Torn ligament, right foot) |
| 5/4 | Darrell Rasner (RHP) - Purchased From Minors |
| 5/4 | Ian Kennedy (RHP) - Sent to Minors (Triple-A) |
| 5/2 | JD Closser (C) - Signed to a Minor League Contract |
| 5/2 | Wilson Betemit (SS) - Sent to Minors, For Rehabilitation |
| 5/2 | Jose Veras (RHP) - Called Up from Minors |
| 5/1 | Phil Hughes (RHP) - Placed on 15-Day DL, (Stress Fracture - Rib Cage) |
APRIL 2008
| Date | Transaction |
| 4/30 | Chad Moeller (C) - Signed as Free Agent, (2008) |
| 4/30 | Chris Stewart (C) - Sent Down to Minors (Triple A S/W-B) |
| 4/30 | Sean Henn (LHP) - Designated for Assignment |
| 4/30 | Sean Henn (LHP) - Removed From 15-Day DL, (Left shoulder tendinitis) |
| 4/30 | Sean Henn (LHP) - Recalled From Minors, Rehab Assignment |
| 4/30 | Chris Britton (RHP) - Called Up from Minors (Triple A S/W-B) |
| 4/30 | Alex Rodriguez (3B) - Placed on 15-Day DL, (Reaggravated right quad strain) |
| 4/29 | Chris Britton (RHP) - Sent Down to Minors (Triple A S/W-B) |
| 4/29 | Edwar Ramirez (RHP) Called Up from Minors (Triple A S/W-B) |
| 4/29 | Chris Stewart (C) - Purchased From Minors |
| 4/28 | Jorge Posada (C) - Placed on 15-Day DL, (Right shoulder pain) |
| 4/26 | Shelley Duncan (OF) - Called Up from Minors (Triple A S/W-B) |
| 4/26 | Billy Traber (LHP) - Sent Down to Minors (Triple A S/W-B) |
| 4/25 | Jonathan Albaladejo (RHP) - Called Up from Minors (Triple A S/W-B) |
| 4/25 | Chris Britton (RHP) - Called Up from Minors (Triple A S/W-B) |
| 4/25 | Chad Moeller (C) - Designated for Assignment |
| 4/19 | Edwar Ramirez (RHP) - Sent Down to Minors (Triple A S/W-B) |
| 4/19 | Joba Chamberlain - Removed from the Bereavement List |
| 4/19 | Kyle Farnsworth (RHP) - Three Game Suspension Announced By League |
| 4/18 | Edwar Ramirez (RHP) - Called Up from Minors |
| 4/18 | Jonathan Albaladejo (RHP) - Sent to Minors (AAA-S/WB) |
| 4/14 | Jonathan Albaladejo - Called Up from Minors |
| 4/14 | Wilson Betemit - Placed on 15-Day DL, (Conjunctivitis) |
| 4/14 | Joba Chamberlain - Placed on Bereavement List |
| 4/14 | Chad Moeller - Purchased From Minors |
| 4/14 | Humberto Sanchez - Transferred to 60-Day DL, (Recovery from right elbow surgery) |
| 4/9 | Alberto Gonzalez - Called Up from Minors |
| 4/9 | Shelley Duncan - Reinstated From League Suspension |
| 4/9 | Shelley Duncan - Sent to Minors |
| 4/8 | Sean Henn - Sent to Minors, For Rehabilitation |
| 4/6 | Melky Cabrera - Reinstated From League Suspension |
| 4/6 | Shelley Duncan - Starting to Serve Suspension |
| 4/5 | Jonathan Albaladejo - Sent to Minors |
| 4/5 | Andy Pettitte - Removed From 15-Day DL, (Back spasms) |
| 4/4 | Melky Cabrera - Starting to Serve Suspension |
MARCH 2008
| Date | Transaction |
| 3/29 | Andy Pettitte placed on 15-Day DL (retroactive to 3/22), (Back spasms). Will be activated on April 5 |
| 3/29 | Reassigned pitchers Kei Igawa, Edwar Ramirez and Jose Veras |
| 3/29 | Humberto Sanchez Placed on 60-Day DL, (Recovery from right elbow surgery) |
| 3/27 | Reassigned INF Cody Ransom, OF Jason Lane, C Jason Brown, OF Greg Porter, OF Brett Gardner and INF Bernie Castro to Minor League camp |
| 3/26 | Released nonroster invitee IF Chris Woodward |
| 3/24 | Reassigned RHP Scott Strickland to Minor League camp |
| 3/23 | Optioned RHP Chris Britton to Triple-A Scranton/Wilkes-Barre; Reassigned RHP Dan Giese and LHP Heath Phillips to Minor League camp |
| 3/22 | Added INF Morgan Ensberg to 40-man roster; Placed RHP Carl Pavano on the 60-day disabled list |
| 3/20 | Reassigned C Kyle Anson to Minor League camp |
| 3/14 | Reassigned RHP Scott Strickland to Major League camp; Released INF Billy Crystal |
| 3/14 | Shelley Duncan suspension announced, (three games), Melky Cabrera suspension announced, (three games) |
| 3/12 | Added LHP Billy Traber to the 40-man roster; transferred RHP Andrew Brackman to the 60-day disabled list |
| 3/12 | Signed IF Billy Crystal to a Minor League contract with an invitation to Spring Training; optioned RHPs Jeff Marquez, Steven White and LHP Chase Wright to Triple-A Scranton/Wilkes-Barre; optioned C Francisco Cervelli to Double-A Trenton. |
| 3/11 | Optioned IF Juan Miranda to Triple-A Scranton/Wilkes-Barre and reassigned him to Minor League camp; reassigned OFs Colin Curtis, Austin Jackson and Jose Tabata, and C P.J. Pilittere to Minor League camp |
| 3/10 | C Chad Moeller signed to a Minor League Contract |
| 3/10 | reassigned RHP Alan Horne, RHP Jeff Marquez and LHP Chase Wright to Minor League camp |
| 3/8 | Reassigned RHP Steven Jackson, RHP Daniel McCutchen, RHP Mark Melancon and 3B Marcos Vechionacci to Minor League camp; Optioned RHP Steven White to Triple-A Scranton/Wilkes-Barre |
| 3/3 | Reassigned INF Marcos Vechionacci to Minor League camp |
| 3/2 | Reassigned INF Eric Duncan and INF Eduardo Nunez to Minor League camp |
| 3/1 | Reassigned C Jesus Montero and C Austin Romine to Minor League camp |